Cell Division: Centrosomes Have Separation Anxiety

When fate follows age: unequal centrosomes in asymmetric cell division

A strong correlation between centrosome age and fate has been reported in some stem cells and progenitors that divide asymmetrically. In some cases, such stereotyped centrosome behaviour is essential to endow stemness to only one of the two daughters, whereas in other cases causality is still uncertain. Here, we present the different cell types in which correlated centrosome age and fate has be...

Separation anxiety

Since the discovery of the CTR1 protein kinase and the endoplasmic reticulum (ER)-localized EIN2 protein nearly 20 y ago, plant biologists have wondered how these proteins respectively serve as negative and positive regulators of ethylene-mediated signal transduction in plants. Now with the publication of four studies, it can be concluded that in the absence of ethylene (ET) in Arabidopsis thal...

Chromosomal Diseases in Humans (1): Cell Division

This article has no abstract.

Centrosomes lead stem cell orientation

tem cells in the fly male germ line can both maintain their numbers and produce differentiating progeny by correctly orienting cell division, according Asymmetric cell division is associated with control over spindle orientation in several models, such as the fly neuroblast and the worm P1 cell. In both of these cases, the spindle is reoriented during mitosis. But in fly germline stem cells (GS...

Separation anxiety: an overview.